According to a recent report in the American magazine Magnesium Monthly Review, researchers at the School of Advanced Materials Engineering at Kookmin University in South Korea and several other Korean research centers announced that their researchers have developed a magnesium-based orthopaedic implant material that can perform in humans. Safely degrades and promotes bone formation.

    In the past 10 years, numerous studies have been done to control the mechanical and corrosion properties of magnesium-based alloys, which degrade in physiological environments. The goal is to overcome the shortcomings of inert implant materials and change the paradigm of traditional bone fixation devices.

    Controlled degradation of the Mg-5Ca-IZn alloy formed at the degradation interface - biomimetic formation of a calcified matrix, initiating a bone formation process that promotes early bone healing and can be completely replaced by new bone within one year of implantation Degradation of magnesium implant materials.

    There have been 53 successful long-term clinical studies.

    The study showed that over a year of clinical trials, the magnesium alloy gradually degraded and the implant material was almost indistinguishable. When degradation begins, new bone grows in place, the chemical composition of the interface closest to the implant material-bone shows Mg(OH)2, and the crystalline product mimics the body's natural calcified matrix, causing resorption of osteoclasts, which are broken by Osteocytes stimulate bone formation. The continuous degradation process of magnesium alloys and the formation of bone causes the disappearance of the implant material and the appearance of new bone.